The clinical spectrum of Nocardia brasiliensis infection in the ... | 合法醫療器材資訊網

由RASmegoJr著作·1984·被引用175次—SevencasesofinfectionduetoNocardiabrasiliensiswereidentifiedovera13-​yearperiodatDukeUniversityMedicalCenter,Durham,NorthCarolina.

Seven cases of infection due to Nocardia brasiliensis were identified over a 13-year period at Duke University Medical Center, Durham, North Carolina. These seven cases and a review of 55 cases in the literature reported from the United States show that N. brasiliensis can cause a wide spectrum of disease. Forty-six of the 62 patients had disease of skin and soft tissues. Cutaneous manifestations included cellulitis, pustules, ulcerations, pyoderma, subcutaneous abscesses, a lymphocutaneous syndrome, and mycetoma. Six patients had pleuropulmonary disease, and one patient had isolated central nervous system (CNS) involvement. Dissemination of disease, a characteristic generally attributed to Nocardia asteroides infection, was seen in eight instances. Patient ages ranged from one to 79 years; 51 of the patients were males. N. brasiliensis was an opportunistic pathogen in only 28% of the cases for which adequate clinic...