The Mechanism of Ovulation | 合法醫療器材資訊網

Gonadotropinreleasinghormone(GnRH)·Folliclestimulatinghormone(FSH)·Luteinizinghormone(LH)·Twocells–twogonadotropins·Estradiol·Progesterone.

The normal functioning of this axis is dependent on the correct synchronization of the timing of release and the quantity of the hormones involved. These change dramatically throughout the cycle as a result of the various feedback mechanisms involved. First, we will consider the individual hormones involved, their target organs and actions, before piecing together the mosaic of the feedback mechanisms to complete the hormonal profile of the normal ovulatory cycle. Fig. 1 provides a very simple representation of the origin, target organ and feedback mechanisms of the principal hormones involved in this axis.

Fig. 1. A simple diagrammatic representation of the origins, target organs and feedback mechanisms of the principal hormones involved in the hypothalamic-pituitary-ovarian axis.

Gonadotropin releasing hormone (GnRH)

GnRH is a decapeptide which is synt...