Is blood superior to crystalloid cardioplegia? A meta | 合法醫療器材資訊網

由VGuru著作·2006·被引用206次—Bloodcardioplegiaprovidessuperiormyocardialprotectionascomparedwithcrystalloidcardioplegia,includinglowerratesofLOS,andearly ...

Background: Many small, randomized, controlled trials have evaluated the effectiveness of blood as compared with crystalloid cardioplegia for myocardial protection during cardiac surgery. Blood cardioplegia provides a closer approximation to normal physiology, which may translate into measurable clinical benefits. This meta-analysis describes the effectiveness of blood cardioplegia in lowering adverse postoperative outcomes.

Methods and results: MEDLINE, EMBASE, and the Cochrane registry of controlled trials were searched for clinical trials. The search was restricted to peer-reviewed English language publications of randomized controlled trials that primarily compared blood and crystalloid cardioplegia in adult patients. Each trial was blindly assessed and abstracted by 2 reviewers. The primary outcomes were: low output syndrome (LOS), myocardial infarction (MI), and death. Surrogate outcomes inclu...