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The inflammatory cells were more numerous in samples obtained from the drilled sites (Fig. 1). Neo-osteogenesis was quantified by considering the absolute number of osteoblasts per high-power field (mean of 10 fields) in osteo-genetic areas; it was consistently more active in the bone samples from the implant sites prepared using the piezoelectric bone surgery technique (Fig. 2).

Preti G., Martinasso G., Peirone B., Navone R., Manzella C., Muzio G., Canuto R.A., Schierano G. "Cytokines and Growth Factors Involved the Osseointegration of Oral Titanium Implants Positioned using Piezoelectric Bone Surgery versus a Drill Technique: a Pilot Study in Minipigs." J Periodontol. 2007 Apr; 78(4):716-22