Antithrombotic therapy in patients with mechanical and ... | 合法醫療器材資訊網

由PDStein著作·2001·被引用394次—Permanenttherapywithoralanticoagulantsoffersthemostconsistentprotectionin...heartvalves,includingpatientsinsinusrhythmwithSt.JudeMedicalvalvesin…...fortiltingdiskvalvesandbileafletpros

1. Permanent therapy with oral anticoagulants offers the most consistent protection in patients with mechanical heart valves. 2. Antiplatelet agents alone do not consistently protect patients with mechanical prosthetic heart valves, including patients in sinus rhythm with St. Jude Medical valves in the aortic position. 3. Levels of oral anticoagulants that prolong the INR to 2.0 to 3.0 appear satisfactory for patients with St. Jude Medical bileaflet and Medtronic-Hall tilting disk mechanical valves in the aortic position, provided they are in sinus rhythm and the left atrium is not enlarged. Presumably, this is also true for the CarboMedics bileaflet valve, based on the observation of no clinically important difference in the rate of systemic embolism with this valve and the St. Jude Medical bileaflet valve. 4. Levels of oral anticoagulants that prolong the INR to 2.5 to 3.5 are satisfactory for tilting disk valves ...