Detection of IgG anti | 合法醫療器材資訊網
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由SSpitalnik著作·1985·被引用17次—Lewisbloodgroupantibodiesrarely,ifever,causehemolyticdiseaseofthenewborn.ThisobservationhasbeenattributedtotheabsencebothofLewis ...
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Lewis blood group antibodies rarely, if ever, cause hemolytic disease of the newborn. This observation has been attributed to the absence both of Lewis antigens on fetal cells and of maternal IgG Lewis antibody. In the present study, sera from 13 mother-infant pairs were tested for the presence of anti-Lewis (a) by hemagglutination and by a sensitive and specific kinetic enzyme-linked immunosorbent assay. By routine hemagglutination methods, anti-Lea was present in all maternal samples but absent in all cord samples. By kinetic enzyme-linked immunosorbent assay, IgG anti-Lea was present in 13 of 13 maternal samples and in 12 of 13 cord samples. These results indicate that IgG anti-Lea antibodies are common and do cross the placenta. This suggests that they do not cause hemolytic disease of the newborn because of the low levels of Lewis antigens on fetal red cells.
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【"羅倫" 單株抗體抗Lea血清試劑】許可證字號:衛部醫器輸字第032130號
器材品名:"羅倫"單株抗體抗Lea血清試劑許可證字號:衛部醫器輸字第032130號註銷狀態:註銷日期:註銷理由:有效日期:2024/01/21...