Comparison of Spectra Optia and COBE Spectra apheresis ... | 合法醫療器材資訊網

由JKim著作·2016·被引用13次—PerformancecharacteristicsofSpectraOptiaforHbS,HctandFCRweresimilartoCOBESpectraforIHD-RBCx.IHD-RBCxprocedureonOptiarequiredless ...

Background: Spectra Optia (Terumo BCT, Lakewood, CO) was FDA approved for red blood cell exchange (RBCx) procedures in January 2014 and is expected to replace COBE spectra (Terumo BCT) very soon in the USA. The performance characteristics of these devices for Isovolemic Hemodilution (IHD-RBCx) procedure were compared in this study.

Methods: A total of 114 IHD-RBCx procedures from 19 patients were analyzed. For every patient, three procedures on each device with similar pre-procedure hematocrits were compared. Pre and post procedure laboratory parameters compared were hemoglobin S (HbS), hematocrits (Hct), platelet counts and fraction of cells remaining (FCR). Statistical analysis was performed using t-test adjusted by the Holm-Bonferroni method to reduce family-wise error rate.

Results: There were no significant differences between these two devices in regards to HbS, Hct, FCR and p...