Overview of Mechanical Ventilation | 合法醫療器材資訊網

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Normal spontaneous breathing generates negative intrapleural pressure, which creates a pressure gradient between the atmosphere and the alveoli, resulting in air flowing inward. In mechanical ventilation, the pressure gradient results from increased (positive) pressure of the air source.

Peak airway pressure is measured at the airway opening (Pao) and is routinely displayed by mechanical ventilators. It represents the total pressure needed to push a volume of gas into the lung and is composed of pressures resulting from inspiratory flow resistance (resistive pressure), the elastic recoil of the lung and chest wall (elastic pressure), and the alveolar pressure present at the beginning of the breath (positive end-expiratory pressure [PEEP]—see figure Components of Airway Pressure[1]). Thus,