APOB Gene - GeneCards | 合法醫療器材資訊網

APOB (Apolipoprotein B) is a Protein Coding gene. Diseases associated with APOB include Hypobetalipoproteinemia, Familial, 1 and Hypercholesterolemia, ... Read More

2021年5月18日 — The APOB gene provides instructions for making two versions of the apolipoprotein B protein, a short version called apolipoprotein B-48 and a ... Read More

2021年6月7日 — ApoB is the main protein of chylomicrons, LDL and VLDL, and acts as a ligand for LDL receptors for cholesterol uptake and LDL catabolism in ... Read More

2021年5月9日 — This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 ... Read More

Genetic disorders — Apolipoprotein B (ApoB) is a protein that in humans is encoded by the APOB gene. Contents. 1 Function; 2 Genetic disorders; 3 ... Read More

由 AJ Whitfield 著作 · 2004 · 被引用 220 次 — The 43-kb APOB gene is located on the short arm of human chromosome 2. It consists of 29 exons, of which exon 26, at 7572 bp, is the largest ... Read More

由 AJ Whitfield 著作 · 2004 · 被引用 220 次 — Missense mutations in the LDL-receptor-binding domain of apoB cause familial ligand-defective apoB-100, characterized by hypercholesterolemia and ... Read More

由 RV Farese Jr 著作 · 1992 · 被引用 75 次 — More than 20 different mutations in the apoB gene have been shown to cause familial hypobetalipoproteinaemia, a condition characterized by abnormally low ... Read More

Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (​apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal ... Read More

HGNC Approved Gene Symbol: APOB. Cytogenetic ... Apolipoprotein B is the main apolipoprotein on chylomicrons and low density lipoproteins (LDLs). It occurs ... Read More