Neurostimulation | 合法醫療器材資訊網

Neurostimulationtherapiesworkbyactivatingorinhibitingexcitabletissue,suchasthenervoussystemorheart,throughthedeliveryofelectricalcurrentsthrough​ ...

Neurostimulation is the electrical process of inhibition, stimulation, modification, regulation, or therapeutic alteration of activity in the central, peripheral, or autonomic nervous systems. It is inherently nondestructive, reversible, and adjustable. Various neurostimulators are used as therapies. A deep brain stimulator is an electrical stimulator that discharges electrical current within the globus pallidus of the basal ganglia or subthalamic nucleus of the diencephalon, as a treatment for some of the symptoms of advanced levodopa-responsive Parkinson’s disease that are not adequately controlled by medications.

Normally, pigmented midbrain neurons in the substantia nigra pars compacta project to the putamen and caudate, where they release dopamine. When more than half of the dopaminergic nerve terminals in the striatum are gone, the motor impairments of Parkinson’s disease arise. The mechanisms underly...