Continuous renal replacement therapy in critically ill patients | 合法醫療器材資訊網

由CRonco著作·2001·被引用142次—Continuousrenalreplacementtherapyincriticallyillpatients.NephrolDialTransplant.2001;16Suppl5:67-72.doi:10.1093/ndt/16.suppl_5.67.

Acute renal failure is an evolving syndrome in which new pathogenetic mechanisms have recently been elucidated. The evolution of the field of haemodialysis has led to a parallel development in the therapeutic approach to patients suffering from this syndrome. In particular, acute renal failure is more frequently seen as part of a more complex syndrome, defined as multiple organ failure. In this clinical setting, patients are almost inevitably confined to intensive care units and sepsis is a frequent underlying mechanism of organ failure. The use of new devices and new machines, together with a better understanding of the underlying mechanisms of solute and water removal, have allowed us to achieve higher levels of efficiency and clinical tolerance during artificial renal replacement therapy. The first objective has been reached by increasing the automation of the extracorporeal circuits and the operational levels of...