Clarifying the confusion of GFRs | 合法醫療器材資訊網

由JGToffaletti著作·被引用1次—SeveralreportsalsoindicatethatcystatinCisbetterthancreatinineforpredictingriskincardiovasculardisease[14],althoughotherstudiesdidnotconcludethat ...

Abbreviations: GFR = glomerular filtration rate; mGFR = measured GFR; eGFR = estimated GFR; MDRD = Modification of Diet in Renal Disease; CKD-EPI = Chronic Kidney Disease Epidemiology Collaboration; C-G = Cockcroft-Gault; IDMS = isotope dilution mass spectrometry; CKD = chronic kidney disease

Many methods for assessing kidney function have been developed over the past century, most notably measurements of serum creatinine, glomerular filtration rate (GFR), urea, and cystatin C. Determining the measured GFR (mGFR) requires measurement of an endogenous marker such as creatinine [1], or an exogenous marker such as inulin [2], iothalamate, 51Cr-EDTA, or iohexol. However, all techniques for measuring GFR are time-consuming and tedious.

Measurement of serum creatinine and cystatin C are more convenient and rapid tests for evaluating kidney function. Especially for within-in...