Clinical guidelines for diagnosis and treatment of ... | 合法醫療器材資訊網

Prolactinomaisthemostcommonpituitaryadenomainchildrenandadolescents.Virtuallyallprolactinomasdiagnosedinchildrenareasymptomatic,andshould ...

These guidelines were based on a literature review of original papers, meta-analyses, and clinical guidelines prepared by expert groups of recognized competence, supplemented by our views and personal experiences. Whenever possible, the available evidence on each subject has been categorized based on the grades of recommendation (GRADE system) used by the Endocrine Society in preparing its clinical guidelines. This system includes two grades of recommendation (1: strong, or 2: weak) and classifies the quality of evidence into one of four categories (⊕⊕⊕⊕: high, ⊕⊕⊕○: moderate, ⊕⊕○○: low, or ⊕○○○: very low). As with other subjects related to neuroendocrinology, it should be taken into account that little high-quality evidence is available in many aspects.