Polyvinyl Alcohol Particles | 合法醫療器材資訊網

2016年12月3日—PolyvinylAlcoholParticles...Polyvinylalcohol(PVA)isoneoftheoldest,particulateembolicmaterialsprovidinginexpensive,permanent ...

Ajita Deodhar • John A. Kaufman

Polyvinyl alcohol (PVA) is one of the oldest, particulate embolic materials providing inexpensive, permanent occlusion of blood vessels. It is a water-soluble, colorless synthetic polymer made from polyvinyl acetate through partial or full hydrolysis to remove the acetate groups. The extent of hydroxylation determines the physical, chemical, and mechanical properties of the PVA.1 Typically, PVA is highly soluble in water but resistant to most organic solvents, which allows it to be used for many applications, including paper manufacturing, cosmetics, household sponges, food packaging, and medical devices.2 The first ever medical use of PVA was reported by Grindlay3 in 1949 at the Mayo Clinic as a prosthesis after pneumonectomy. Since then, it has found multiple medical applications such as cardiac surgery, skin grafting, embolic material, a...