Carbohydrate antigen 19 | 合法醫療器材資訊網

由SKim著作·2020·被引用7次—CA19-9isoftenelevatedinbenignpancreatobiliarydiseasessuchascholangitis,obstructivejaundiceandpancreatitis.Additionally,ithasbeen ...

CA 19-9 is a tumor marker that is frequently checked in healthy individuals when screening for various cancers including pancreatic cancer5,6,7,8. In addition to malignancies, it is known that CA 19-9 may also increase in benign pancreatobiliary, hepatic and pulmonary diseases, thyroiditis, diabetes mellitus, and autoimmune diseases. Therefore, we should be cautious in interpreting the significance of CA 19-9 elevation5,13.

The reason for CA 19-9 elevation in benign disease can be explained by several mechanisms. First of all, inflammation and proliferation of non-tumorous tissue, such as in pancreatitis, cholangitis, bronchiectasis, idiopathic pulmonary fibrosis, ovarian cyst, and endometriosis, can elevate CA 19-9. CA 19-9 also increases as a result of obstructive jaundice and bronchitis as CA 19-9 excretion is blocked in these diseases. The last mechanism is when metabolic malfunction is present ...