Cardiac Resynchronization Therapy. Indications ... | 合法醫療器材資訊網

Patientswererandomlyassignedina1:2:2ratiotopharmacologicaltherapyalone,CRTonly(CRT-P),orCRTplusdefibrillator(CRT-D),respectively.

Progress in medical therapy wouldn’t be possible without the contribution of the scientific community. Several randomized controlled trials have led to our current guidelines. Specifically, COMPANION and CARE-HF trials involved a turning point for cardiac resynchronization therapy, which became well recognized for the treatment of heart failure patients with QRS≥120ms, ejection fraction≤35%, and sinus rhythm to reduce hospitalizations and all-cause mortality. New indications were then established for atrial fibrillation, pacemaker-dependent, and mildly symptomatic patients, but new challenges should be addressed, namely reducing complication and nonresponder rates. To achieve this, further studies and new implant techniques are under investigation.