What is partial thromboplastin time (PTT) and activated partial ... | 合法醫療器材資訊網

2019年7月30日—Partialthromboplastintime(PTT)andactivatedpartialthromboplastintime(aPTT​)areusedtotestforthesamefunctions;however,inaPTT, ...

Partial thromboplastin time (PTT) and activated partial thromboplastin time (aPTT) are used to test for the same functions; however, in aPTT, an activator is added that speeds up the clotting time and results in a narrower reference range. The aPTT is considered a more sensitive version of the PTT and is used to monitor the patient’s response to heparin therapy.

The aPTT test is used to measure and evaluate all the clotting factors of the intrinsic and common pathways of the clotting cascade by measuring the time (in seconds) it takes a clot to form after adding calcium and phospholipid emulsion to a plasma sample. The result is always compared to a control sample of normal blood.

The aPTT evaluates factors I (fibrinogen), II (prothrombin), V, VIII, IX, X, XI and XII. (A retrospective study by Bachler et al indicated that in critically ill patients, a factor XII lev...