Hyperprolactinemia | 合法醫療器材資訊網

2020年4月10日—Hyperprolactinemiaisaconditionofelevatedserumprolactin.Prolactinisa198-​aminoacidprotein(23-kd)producedinthelactotrophcellsof ...

Hyperprolactinemia is a condition of elevated serum prolactin. Prolactin is a 198-amino acid protein (23-kd) produced in the lactotroph cells of the anterior pituitary gland. Its primary function is to enhance breast development during pregnancy and to induce lactation. However, prolactin also binds to specific receptors in the gonads, lymphoid cells, and liver. [1]  Hyperprolactinemia can be assessed through laboratory and imaging studies. Medical therapy is the treatment of choice for symptomatic patients. [2]

Secretion is pulsatile; it increases with sleep, stress, pregnancy, and chest wall stimulation or trauma and therefore must be drawn after fasting. Normal fasting values are generally less than 25-30 ng/mL, depending on the individual laboratory, but can also vary for a number of reasons. Normal levels are also generally higher in women.

Nonpuerperal hyperprolactinemi...