Hydrogel dressing | 合法醫療器材資訊網

Hydrogeldressingsareahydrogelpadincontactwiththewound.Thehydrogelisahydratedthree-dimensional(3D)networkconsistingofphysicallyor ...

Hydrogels are three-dimensional networks consisting of chemically or physically cross-linked hydrophilic polymers.[1] The insoluble hydrophilic structures absorb polar wound exudates and allow oxygen diffusion at the wound bed to accelerate healing.[2] Hydrogel dressings can be designed to prevent bacterial infection, retain moisture, promote optimum adhesion to tissues, and satisfy the basic requirements of biocompatibility.[1][2] Hydrogel dressings can also be designed to respond to changes in the microenvironment at the wound bed.[3] Hydrogel dressings should promote an appropriate microenvironment for angiogenesis, recruitment of fibroblasts, and cellular proliferation.[2][4]

Hydrogels respond elastically to applied stress; gels made from materials like collagen exhibit high toughness and low sliding friction, reducing damage from mechanical stress.[1][5] Hydrogel dressings should possess mechan...