Evaluation of Gastroesophageal Reflux Disease Using the ... | 合法醫療器材資訊網

由RMALawenko著作·2016·被引用19次—TheBravopHmonitoringsystemisasafeandwell-toleratedalternativetothecatheter-basedpHmonitoring.Itispatient-friendlywiththeability ...

Gastroesophageal reflux disease (GERD) is on the increase in Asia with prevalence ranging from 5% up to 18%.1 Heartburn and regurgitation are typical symptoms of GERD, but are unreliable in terms of distinguishing GERD from functional gastrointestinal (GI) diseases particularly among Asians.2,3 In addition, the presence of reflux symptoms lack direct correlations with increased esophageal acid exposure, as well as endoscopically proven esophagitis.2,3

In a symptomatic Asian patient with normal endoscopic findings, the diagnosis of GERD would often rely on documented high esophageal acid exposure. Ambulatory 24-hour pH monitoring, first introduced in 1974, was developed to detect abnormal levels of acid reflux in the lower esophagus.4,5 Conventional pH monitoring requires a nasopharyngeal catheter with pH electrode placed 5 cm above the lower esophageal sphincter to document distal esophageal acid exposure and correlate this with reflux symptoms.5 Although highly ...