Natural Killer Cell Markers | 合法醫療器材資訊網
ThreesubsetsofmouseNKcellshavebeencharacterizedbasedonthedifferentialexpressionofIntegrinalphaM/CD11bandCD27.TheseincludeCD11dim ...
OverviewNatural killer (NK) cells[1] are innate lymphoid cells with both intrinsic cytotoxic potential and cytokine-producing capabilities that have been classified as group 1 ILCs. NK cells activation occurs following the detection of abnormalities in target cells, including cells infected with certain bacteria, virally infected cells and cancer. While NK cells share many features with ILC1s including expression of the transcription factor T-bet and activation-induced production of IFN-gamma and TNF-alpha, they also express the transcription factor, eomesodermin (Eomes), along with granzyme B and perforin, which ILC1s do not. Accordingly, NK cells have been suggested to be the innate counterpart of CD8+ T cells[2].
Mouse Cell Surface MarkersIn mice, NK cells are defined as CD3-NK1.1+ or CD3-NKp46+ cells that also typically express Integrin alpha 2/CD49b[3], Integrin al...
Cell Markers | 合法醫療器材資訊網
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Natural Killer Cell Markers | 合法醫療器材資訊網
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