Hyalgan (Hyaluronate): Uses, Dosage | 合法醫療器材資訊網

DirectionsForUse.Hyalgan®isadministeredbyintra-articularinjection.Atreatmentcycleconsistsoffiveinjectionsgivenatweeklyintervals.Somepatientsmay ...

The use of Hyalgan® as a treatment for pain in OA of the knee was investigated in a multicenter clinical trial conducted in the United States.

This study was a double-masked, placebo and naproxen-controlled, multicenter prospective clinical trial with three treatment arms, as summarized in Table 2. A total of 495 subjects with moderate to severe pain was randomized (at baseline evaluation) into three treatment groups in a ratio of 1:1:1 Hyalgan®, placebo, or naproxen.

TABLE 2 STUDY DESIGN