Activated Clotting Time | 合法醫療器材資訊網

2019年11月27日—Description.Activatedclottingtime(ACT)isapoint-of-carecoagulationtestdesignedtomonitorheparintherapyintheclinicalsituationsinwhich ...

Activated clotting time (ACT) is a point-of-care coagulation test designed to monitor heparin therapy in the clinical situations in which intensive anticoagulation is required. [2] Similar to partial thromboplastin time (PTT), ACT reflects time of clot formation via the intrinsic coagulation pathway by the addition of factor XII activators (eg, diatomaceous earth [Celite], kaolin, glass beads, ellagic acid) and increases linearly to relation to the heparin concentration. Clotting times may also vary between ACT analyzers manufactured by different (or the same) vendors, depending on the source and the formula of the activator, the amount of activator relative to the sample volume, or the method of clot detection. Therefore, instrument-specific protocols should be established and validated for each type of clinical procedure. [3]

ACT is used for bedside or intraoperative monitoring of unfra...